Susceptibility Patterns in Pseudomonas aeruginosa Causing Nosocomial Infections

Abstract

Nosocomial infection caused by Pseudomonas aeruginosa has not been eported previously in the Gaza Strip. This study aims to determine the distribution f antimicrobial drug resistance in P. aeruginosa causing nosocomial nfections. One hundred thirty-one P. aeruginosa isolates were collected from arious nosocomial infection clinical samples. The study was conducted etween April and October 2003. The results of this study reveal that the most ommon resistance was to ampicillin, followed by cephalexin. The most effective ntimicrobial agents were meropenem and amikacin, respectively. The ighest resistance to ciprofloxacin was found among ICU and surgery sections. he data analysis shows that no remarkable difference was reported with espect to previous admission and prior antimicrobial treatment for most antibiotics.

The results of this study emphasize the need for constant monitoring of ntimicrobial effectiveness to correctly guide empiric therapy and local intervention rograms in an attempt to reduce antimicrobial resistance.

Keywords:

• Antimicrobial resistance
• nosocomial infection
• Pseudomonas aeruginosa