Gram-Negative Non-Fermenting Bacteria from Food-Producing Animals are Low Risk for Hospital-Acquired Infections

Abstract

The aim of this study was to investigate possible indications of epidemiological relationships between Pseudomonas aeruginosa and Acinetobacter baumannii isolated from food-producing animals and those of clinical origin. Screening for P. aeruginosa and A. baumannii isolates from food-producing animals was carried out on 1381 samples. usceptibility testing and PCR amplification of resistance genes were determined. Isolate clonal relatedness was established by PFGE. Forty-one P. aeruginosa and 16 A. baumannii were detected. All P. aeruginosa isolates were sensitive to ciprofloxacin, ceftazidime and piperacillin/tazobactam and seven isolates had low-level imipenem resistance. All A. baumannii isolates were sensitive to imipenem, meropenem, ciprofloxacin and piperacillin/tazobactam but were resistant to ceftazidime. The imipenem-resistant P. aeruginosa and ceftazidime-resistant A. baumannii had different PFGE patterns compared to those of human origin. Based on the findings presented here, animal isolates were not multidrug resistant and they do belong to a different pool from those of humans.

Keywords:

• Gram-negative
• A. baumannii
• P. aeruginosa
• animal
• human
• antibiotic
• resistance