Abstract
This is a review of laboratory and clinical research studies that have investigated the effects of therapeutic modalities on wound healing. The modalities reviewed include: ultraviolet light, ultrasound, laser, electrical stimulation, and electromagnetic fields on wound healing. Using information gleaned from a review of the present animal and cell culture research, cellular and systemic mechanisms by which these modalities alter the wound healing cascade are postulated. A critical appraisal of the clinical research available that supports the use of each of these modalities to treat chronic wounds has also been provided. This information will be useful when making a choice of the best therapeutic modality to be used to accelerate wound closure of a patient with a chronic skin ulcer.