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Abstract
A monitored dosage system (MDS) is a professionally prepared blister-type repackaging system used to improve medication adherence. The objective of this study was to determine the stability of enalapril tablets, a widely prescribed drug, commonly used by the elderly but potentially unstable in MDSs. No degradation of enalapril tablets repackaged into MDSs was observed during the 60 day study period.
Transparency
Declaration of funding
This work was supported by Mylan Pharmaceuticals SL, Barcelona, Spain. The authors are fully responsible for all content and editorial decisions for this manuscript.
Declaration of financial/other relationships
H.R.L., P.M., C.F.L., A.J.B., G.T., and E.L.M. have disclosed that they have no significant relationships with or financial interests in any commercial companies related to this study or article. The authors were not involved in selecting or managing the journal peer review process.
CMRO peer reviewers on this manuscript have no relevant financial or other relationships to disclose.
Acknowledgments
We would like to express our gratitude to Anota SA for kindly providing the MDSs.
Notes
*Innovace is a registered trade name of Merck Sharp & Dohme Ltd, Hoddesdon, Hertfordshire, UK.