Triple tetracycline (‘Deteclo’) as a single dose oral treatment of uncomplicated gonorrhoea in the male

Summary

Two hundred and sixty-nine patients suffering from acute gonococcal urethritis were treated with single oral doses (variable) of a triple tetracycline preparation (‘Deteclo’).

In acute uncomplicated gonorrhoea, it was found that a single-session treatment with 1.2g. 'Deteclo' gave a failure rate of 6.2%. Side-effects were of a gastrointestinal nature and were not a serious hazard at that particular dosage. They were minimised by an antiemetic, viz. promazine hydrochloride or metaclopramide mono-hydrochloride.

It would appear, therefore, that 'Deteclo' has all the advantages of any oral preparation which can be used in a single-session treatment of acute uncomplicated gonorrhoea. It should, therefore, be considered in this light as an effective, convenient, alternative treatment in uncomplicated male gonorrhoea.

Because of frequent and often distressing side-effects, it was not possible to arrive at an acceptable single-session regime using 'Deteclo' in non-specific urethritis.

Key words: :

• Gonorrhoea
• acute
• tetracycline
• triple