Summary
The authors review their experience in treating 131 patients attending a hospital menopause clinic. In women with an intact uterus, oestrogen replacement therapy is given on a cyclical basis (3 weeks on, 1 week off) with added progestogen in the third week. The lowest effective dose of oestrogen is used for the shortest possible time, and patients are encouraged to stop therapy after 6 to 9 months. The risks of endometrial carcinoma and vascular disease with long-term hormone replacement therapy are discussed in the light of recent evidence.
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