Abstract
This article demonstrates that the folded-over 12-run Plackett–Burman design is useful for considering up to 12 factors in 24 runs, even if one anticipates that some two-factor interactions may be significant. The properties of this design are investigated, and a sequential procedure for analyzing the data from such a design is proposed. The performance of the procedure is investigated through the analysis of real and constructed examples and through a small simulation study. Applications to other folded-over Plackett–Burman designs are also briefly discussed.