Identification of Enterocin NKR-5-3C, a Novel Class IIa Bacteriocin Produced by a Multiple Bacteriocin Producer, Enterococcus faecium NKR-5-3

Kohei HIMENODepartment of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University

Koji FUJITADepartment of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University

Takeshi ZENDODepartment of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University

Pongtep WILAIPUNDepartment of Fishery Products, Faculty of Fisheries, Kasetsart University

Naoki ISHIBASHIDepartment of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University

Yoshimitsu MASUDADepartment of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University

Fuminori YONEYAMADepartment of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University

Vichien LEELAWATCHARAMASDepartment of Biotechnology, Faculty of Agro-Industry, Kasetsart University

Jiro NAKAYAMADepartment of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University

Kenji SONOMOTODepartment of Bioscience and Biotechnology, Faculty of Agriculture, Graduate School, Kyushu University;Department of Functional Metabolic Design, Bio-Architecture Center, Kyushu University

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Abstract

The structure of enterocin NKR-5-3C, an anti-listerial bacteriocin produced by a multiple bacteriocin producer, Enterococcus faecium NKR-5-3, was determined. Enterocin NKR-5-3C is a novel class IIa bacteriocin that possesses an YGNGL motif sequence and two disulfide bridges in its structure. It is encoded on gene ent53C together with an 18-amino-acid-residue double glycine leader peptide.

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Related Research Data

Gene Cluster Responsible for Secretion of and Immunity to Multiple Bacteriocins, the NKR-5-3 Enterocins

Source: American Society for Microbiology

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Identification of Enterocin NKR-5-3C, a Novel Class IIa Bacteriocin Produced by a Multiple Bacteriocin Producer, Enterococcus faecium NKR-5-3

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Identification of Enterocin NKR-5-3C, a Novel Class IIa Bacteriocin Produced by a Multiple Bacteriocin Producer, Enterococcus faecium NKR-5-3

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