The Vagotomy Alleviates the Anorectic Effect of an Excess Amount of Dietary Leucine on Rats Fed a Low-Protein Diet

Ryoji YOSHIMURALaboratory of Molecular Nutrition, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University

Yee Yin HODivision of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University

Takafumi MIZUSHIGEDivision of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University;Research Unit for Physiological Chemistry, C-PIER, Kyoto University

Kousaku OHINATADivision of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University

Ryuhei KANAMOTODivision of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University

Abstract

It is well known that large dose of leucine reduces the food intake and causes growth retardation in experimental animals when leucine is given with a low-protein diet. However, the mechanism for the anorectic effect of leucine has not yet been clarified. We demonstrate here that the anorectic effect of leucine was significantly reduced in a vagotomized rat.

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The Vagotomy Alleviates the Anorectic Effect of an Excess Amount of Dietary Leucine on Rats Fed a Low-Protein Diet

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The Vagotomy Alleviates the Anorectic Effect of an Excess Amount of Dietary Leucine on Rats Fed a Low-Protein Diet

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