Total Synthesis of (+)-Paulownin

Momotoshi OkazakiFaculty of Agriculture, Ehime University, Matsuyama790, Japan

Fumito IshibashiFaculty of Agriculture, Ehime University, Matsuyama790, Japan;Faculty of Fisheries, Nagasaki University, Nagasaki852, Japan

Yoshihiro ShutoFaculty of Agriculture, Ehime University, Matsuyama790, Japan

Eiji TaniguchiFaculty of Agriculture, Ehime University, Matsuyama790, Japan;Faculty of Agriculture, Kyushu University, Fukuoka812, Japan

Abstract

(+)-Paulownin, a furofuran lignan from Paulownia tomentosa, was stereoselectively synthesized from (R)-(+)-3-hydroxybutanolide in 12 steps with a yield of 4.4%.

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Total Synthesis of (+)-Paulownin

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Total Synthesis of (+)-Paulownin

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