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Short Communication

Recognition of Osteopontin by Rat Bone Marrow Derived Osteoblastic Primary Cells

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Pages 754-756 | Received 11 Dec 1996, Published online: 12 Jun 2014
 

Abstract

To study the role of osteopontin, we did cell adhesion and ALP assays of rat bone marrow osteoblastic cells (RBMO) on collagen Type I and osteopontin surfaces. The RBMO proved to adhere much more strongly to the osteopontin and to have higher ALP activity on the osteopontin, which suggests that pre-osteoblasts differentiate into osteoblasts that form bone by recognizing osteopontins.

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