Unique Occurrence of the 1CF11 Carbohydrate Epitope in Primate Saliva

Shan-Ming YANGDepartment of Food Science, Faculty of Agriculture, Gifu University

Naoko YOKOIDepartment of Food Science, Faculty of Agriculture, Gifu University

Yoshihiro KANAMARUDepartment of Food Science, Faculty of Agriculture, Gifu University

Osamu TAKENAKAMolecular Biology Section, Primate Research Institute, Kyoto University

Yasuro ATOJIDivision of Veterinary Medicine, Faculty of Agriculture, Gifu University

Yasuo BUNAIDepartment of Forensic Medicine, Gifu University School of Medicine

Isao OHYADepartment of Forensic Medicine, Gifu University School of Medicine

Xong-Guang SONGDepartment of Food Science, Faculty of Agriculture, Gifu University

Satoshi NAGAOKADepartment of Food Science, Faculty of Agriculture, Gifu University

Makoto SHIMIZUDepartment of Applied Biological Chemistry, The University of Tokyo

Goverdhan P. SACHDEVCollege of Pharmacy, University of Oklahoma Health Sciences Center

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Abstract

We examined a large number of individual human and animal saliva samples for the reactivity with 1CF11, a mouse monoclonal antibody previously produced for the characterization of human milk mucin and apparently recognizing a certain carbohydrate antigenic structure shared by various human glycoproteins in secretions. The results obtained here confirm the unique occurrence of 1CF11 epitope in each and every saliva sample from humans and Old world monkeys as well, though a vast variety was observed among individual saliva samples in the immunological reactivity with 1CF11.

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Unique Occurrence of the 1CF11 Carbohydrate Epitope in Primate Saliva

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Unique Occurrence of the 1CF11 Carbohydrate Epitope in Primate Saliva

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