Synthesis of Both Enantiomers of Isorobinal, a Novel Cyclic Monoterpene Isolated from the Astigmatid Mite, Rhizoglyphus sp.

Abstract

Both enantiomers of isorobinal, a cyclic monoterpene isolated from the astigmatid mite (Rhizoglyphus sp.), were synthesized from the enantiomers of perillaldehyde in four steps by using PCC-oxidation of a tertiary allylic alcohol intermediate as the key step.

• isorobinal
• Rhizoglyphus
• terpenoid