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The biosynthesis of fukinolic acid, which had been isolated from the Japanese fuki vegetable, Petasites japonicus, was investigated by feeding selected 13C-labeled compounds to axenic cultures of P. japonicus. [1,2-13C2] sodium acetate and [1-13C] L-tyrosine were incorporated into the fukiic acid sub group, while [3-13C] L-phenylalanine was incorporated into the caffeic acid moiety.
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