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Bioscience, Biotechnology, and Biochemistry Volume 69, 2005 - Issue 6
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Original Articles

Effects of Fenugreek Seed Extract in Obese Mice Fed a High-Fat Diet

Toshiaki HANDALaboratory of Nutraceuticals and Functional Foods Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology
,
Kohji YAMAGUCHILaboratory of Nutraceuticals and Functional Foods Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology
,
Yoshikatsu SONOTechnical Sourcing International, Inc.
&
Kazunaga YAZAWALaboratory of Nutraceuticals and Functional Foods Science, Graduate School of Marine Science and Technology, Tokyo University of Marine Science and Technology
Pages 1186-1188 | Received 14 Oct 2004, Accepted 11 Mar 2005, Published online: 22 May 2014
 
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Abstract

It was found that fenugreek seed extract reduced the body weight gain induced by a high-fat diet in obese mice. The extract decreased plasma triglyceride gain induced by oil administration. The major component of the extract, 4-hydroxyisoleucine, also decreased plasma triglyceride gain. Consequently, fenugreek seed extract is expected to prevent the obesity induced by a high-fat diet.

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