Long Terminal Repeat of the Mushroom Retrotransposon Functions as a Dual Terminator to Transcription

Kazuo SHISHIDODepartment of Life Science, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology

Ryu NOBUSAKADepartment of Life Science, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology

Shinya KANEKODepartment of Life Science, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology

Yoshihiro SATODepartment of Life Science, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology

Ryoko AKIYAMADepartment of Life Science, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology

Yasumasa MIYAZAKIDepartment of Life Science, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology

Motonori NINOMIYADepartment of Life Science, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology

Shiho KATSUKAWADepartment of Life Science, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology

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Abstract

The 474-bp long terminal repeat (LTR) of the basidiomycete Lentinula edodes retrotransposon was found to contain a different type of transcription termination–poly (A)-addition signal on each strand: TATGT- - -TATG- - -TCT, first reported in yeast genes, and an AATAA (or ACATAA)- - -GT(Py)-rich sequence, frequently found in mammalian genes.

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Long Terminal Repeat of the Mushroom Retrotransposon Functions as a Dual Terminator to Transcription

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Long Terminal Repeat of the Mushroom Retrotransposon Functions as a Dual Terminator to Transcription

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