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Abstract
Oxytetracycline (OTC) was added to pelleted (sinking) and extruding (floating) fish feeds by mixing prior to processing or by surface spraying after processing. The feeds were immersed in water with temperatures of 20°C or 30°C for 5 to 25 minutes. Loss of the antiobotic from all medicated feeds continued throughout the 20-minute immersion at both temperatures. Oxytetracycline leached at a higher rate at 30°C than at 20°C. More OTC leached from trout feed than from catfish feed and from sinking feed than from floating feed at 20°C and at 30°C. The rate of oxytetracycline loss from sprayed feeds was much higher than that from mixed feeds.