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Journal of Addictive Diseases Volume 26, 2007 - Issue 3
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RAPID COMMUNICATIONS

Abuse of Buprenorphine in the United States

2003-2005

Meredith Y. Smith PhD Purdue Pharma L.P., Stamford, CT, USA
,
J. Elise Bailey MS Rocky Mountain Poison Control Center, 777 Bannock Street, Mail Code 0180, Denver, CO, 80204, USA
,
George E. Woody MD Treatment Research Institute, 600 Public Ledger Building, 150 South Independence Mall, West, Philadelphia, PA, 19129, USA
&
Herbert D. Kleber MD Columbia University, New York State Psychiatric Institute, Unit 66, 1051 Riverside Drive, New York, NY, 10032, USA
Pages 107-111 | Published online: 04 Oct 2008
 
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Abstract

This study examines trends in the reported abuse of two sublingual buprenorphine products, Subutex® and Suboxone®, in the United States. Quarterly counts of abuse cases were obtained from 18 regional poison control centers (PCCS) for 2003-2005. Seventy-seven abuse cases were reported, of which 7.8 percent involved Subutex®and 92.2 percent involved Suboxone®. The average quarterly ratio of abuse cases per 1,000 prescriptions dispensed was 0.08 (span ± 0.09) for Subutex®, and 0.16 (SD ± 0.08) for Suboxone®. Findings suggest that these sublingual buprenorphine formulations have a low rate of abuse based on toxico-surveillance data.

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