Preclinical compounds for the treatment of overactive bladder

Abstract

Background: Overactive bladder is a prevalent and bothersome condition. Existing pharmacotherapy with antimuscarinics improves symptoms and quality of life but there are certain limitations in efficacy and tolerability. Objective: To review novel, recently patented compounds for the treatment of overactive bladder. Methods: The European Patent Office database was searched for compounds that emerged in the last 3 years. Results/conclusion: Overactive bladder pathophysiology and treatment is an active field of research. Molecules that modulate/inhibit afferent nerve pathways are the focus of interest and the most promising field of overactive bladder drug development.

Keywords::

• overactive bladder
• patents
• preclinical compounds
• treatment