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Patent Evaluations

A novel Syk kinase inhibitor suitable for inhalation: R-343(?) – WO-2009031011

Pages 1469-1472 | Published online: 24 Jun 2009
 

Abstract

The subject of this application is N4-[(2,2-difluoro-4H-benzo[1,4]oxazin-3-one)-6-yl]-5-fluoro-N2-[3-(methylaminocarbonylmethyleneoxy)phenyl]-2,4-pyrimidinediamine xinafoate salt, as well as inhalant formulations of the salt and a process for the preparation of the salt. This salt is probably R-343, a Syk kinase inhibitor being developed under license by Pfizer, an inhaled formulation of which is in Phase I development for the treatment of asthma.

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