16
Views
1
CrossRef citations to date
0
Altmetric
Review

New therapies for the treatment of age-related macular degeneration

&
Pages 333-341 | Published online: 25 Feb 2005
 

Abstract

Age-related macular degeneration (ARMD) is a leading cause of legal blindness in older adults. The visual loss caused by ARMD can be devastating and many of the current treatment modalities are ineffective or only of moderate benefit in preventing the progression of the disease. Furthermore, few treatment options are available to patients with more advanced cases of ARMD. This review highlights some aspects of our current understanding of ARMD and discusses recent patent applications related to the treatment of this disease. In particular, agents that promote retinal pigment epithelium (RPE) cell proliferation and compounds with anti-oxidant properties that may prove useful in the treatment of non-neovascular ARMD will be discussed. In addition, we review photodynamic therapy and anti-angiogenic compounds that show potential promise in the treatment of the neovascular form of ARMD.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.