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Abstract
Blockers of the Kv1.3 channel, a voltage-gated K+ channel found in human T-cells, have recently been recognised as a general strategy for immunosuppression. These blockers are divided into two classes – peptidyl and non-peptidyl Kv1.3 channel blockers. This article covers the patents filed for Kv1.3 channel blockers dating from 1996 to the first quarter of 2000.