![Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days]({"type":"image" , "src" : "/sda/5925/TOC-Subject-Sample-2021-Bioscience.jpg"})
Abstract
A series of benzoic acid derivatives, indicated to be selective RAR-γ agonists, based upon a branched alkyl chain substituted by dimethylchroman or tetrahydronaphthalene rings, are claimed. The claimed compounds are orally-active potent stimulants of alveolar repair and are claimed to be useful in the treatment of emphysema. With activity at daily dosages as low as 1 μg/kg/day the claimed compounds could prove to valuable therapeutic agents.