![Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days]({"type":"image" , "src" : "/sda/5925/TOC-Subject-Sample-2021-Bioscience.jpg"})
Abstract
This application claims aryl-substituted arylsulfonamidophenoxyacetic acid derivatives, and their use for the treatment of allergic and immune disease such as asthma and allergic rhinitis. The claimed compounds represent a novel class of prostaglandin D2 (PGD2) antagonists active at the CRTH2 receptor. The compounds bear some resemblance to older, arylsulfonamide TPreceptor antagonists.