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Novelty: Substituted benzoic acids, benzamides and esters are disclosed for use against HIV. They are said to exhibit nuclear ADP-ribosyl transferase activity and are related to known inhibitors. Potential use in trypanosomiasis and cancer is also claimed.
Biology: There are no detailed biological data to support the claims. Fifteen synthetic examples are included. A typical preferred compound is 4-methylureidobenzamide.
Structure:
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