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Patent Evaluations

Novel 1,5-naphthyridine PI3Kδ inhibitors, an evaluation of WO2011075628

Pages 1805-1810 | Published online: 23 Sep 2011
 

Abstract

A small series of aryl(1-arylamino)ethyl,1,5-naphthyridine derivatives that selectively inhibit PI3Kδ was prepared. The compounds are claimed to be useful in the treatment of cancer, inflammatory and autoimmune diseases. The compounds represent further variations around a structural motif explored in a number of previous applications by the applicant.

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