Pyrazolopyridines as inhibitors of the kinase LRRK2: a patent evaluation (WO2011141756)

Xianming DengDana-Farber Cancer Institute, Harvard Medical School, Department of Biological Chemistry & Molecular Pharmacology, and Department of Cancer Biology, 250 Longwood Ave, SGM 628, Boston, MA 02115, USA+1 617 582 8590; +1 617 582 8615; [email protected];Xiamen University, School of Life Sciences, State Key Laboratory of Cellular Stress Biology, Fujian 361005, China+86 592 218 4180; +86 592 218 1722; [email protected]

Nathanael S. GrayDana-Farber Cancer Institute, Harvard Medical School, Department of Biological Chemistry & Molecular Pharmacology, and Department of Cancer Biology, 250 Longwood Ave, SGM 628, Boston, MA 02115, USA+1 617 582 8590; +1 617 582 8615; [email protected]

Abstract

Scientific evaluation of a patent aiming for the development of pyrazolopyridine derivatives as LRRK2 kinase inhibitors, a potential therapeutic target for combating Parkinson's disease.

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Pyrazolopyridines as inhibitors of the kinase LRRK2: a patent evaluation (WO2011141756)

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Pyrazolopyridines as inhibitors of the kinase LRRK2: a patent evaluation (WO2011141756)

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