Novel sulfonamide compounds for inhibition of metastatic tumor growth (WO2012021963)

Abstract

A series of novel ureido-sulfonamides was prepared by reaction of aminobenzenesulfonamide with alkyl/aryl isocyanate. These compounds are claimed for use as therapeutic agents of metastatic tumors, which are poorly responsive to classical chemotherapies and constitute a conceptually novel approach for cancer treatment.

Keywords::

• antimetastatic agents
• carbonic anhydrase IX
• metastatic tumor
• ureido-sulfonamide