Patent Evaluation: Cyclodextrin polymers for reducing cholesterol concentrations

Summary

Novelty: Cyclodextrin polymers are claimed to be useful for absorbing cholesterol from blood, plasma and food products. Such polymers may be used as a treatment for hyperlipi-daemia.

Biology: The compounds were shown to absorb cholesterol from loops of small intestine in vivo in the rat, from blood plasma and from LDL particles from human blood.

Chemistry: The synthesis of 8 polymers is described and 6 of these are specifically claimed.