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Abstract
Two patent applications by McGeer et al. at the University of British Columbia are discussed. Both patents consider the novel use of different classes of known anti-inflammatory drugs for the treatment of dementia of the Alzheimer's type. The proposals arise from observations made by the authors that the incidence of dementia is lower then expected amongst arthritic patients treated with non-steroidal anti-inflammatory drugs (NSAIDs) and leprosy sufferers administered dapsone. In the case of NSAIDs, the beneficial effects of one such drug, indomethacin, are presented in sufferers from Alzheimer's disease (AD).