Abstract
Ribozyme Pharmaceuticals, Inc. is based on a distinctive technology which uses antisense molecules that are also enzymes. An obvious use of these molecules is in the cleavage of mRNA for genes expressed in disease states or those encoded by infecting viruses. The Company has an impressive portfolio of patented ribozyme sequences relevant to a wide range of disorders, although questions remain over the degree of homology needed to target the enzyme and their stability and activity.