Novel furan sulphonic acid derivatives for the treatment of neurodegenerative and immunoinflammatory disorders

Abstract

Furan sulphonic acid derivatives are claimed to inhibit formation of amyloid β-sheets and/or protect against neuronal cell loss and/or inhibit the release of cytokines, such as IL-1β, IL-6 and TNF-α. Thus, these compounds may be useful for the treatment of neurodegenerative diseases, autoimmune diseases and inflammatory diseases.

• Alzheimer’s disease
• amyloid protein deposition inhibitors
• autoimmune diseases
• cytokine release inhibitors
• furan sulphonic acids
• neurodegenerative diseases