Emerging pharmacological therapies for erectile dysfunction

Abstract

There are new and novel therapies emerging in the field of erectile dysfunction, both centrally acting and peripherally acting agents delivered orally, intracavernosally or topically. Pharmacological targets include the enzyme phosphodiesterase Type 5 (PDE5), adrenergic receptors, prostaglandin receptors and guanyl cyclase.

• adrenoceptor antagonists
• cAMP activators
• dopaminergic agonists
• endothelin antagonists
• melanin stimulating hormone
• nitric oxide donors
• PDE5 inhibitors
• potassium channel modulators