Abstract
On the basis of pharmacological observations, neuropeptide Y (NPY) has been implicated to be involved in numerous physiological functions. Preliminary results suggest a wide therapeutic utility for NPY antagonists in disorders such as anxiety, appetite stimulation, obesity, alcohol intake, hypertension, and regulation of coronary tone. This review will focus on patent applications describing non-peptidic NPY ligands published over the last ten years. Primary publications will be incorporated where appropriate.