Pharmacological testing of anisocoria

Abstract

Anisocoria, or a difference in pupil size, is a common condition. Its aetiology ranges from benign to life-threatening conditions. The clinical evaluation of anisocoria is discussed, emphasising the pharmacological aids (e.g., cocaine 10% eye drops, hydroxyamphetamine eye drops, pilocarpine 0.1% eye drops, pilocarpine 1% eye drops, apraclonidine) used in differentiating the different causes of anisocoria (e.g., physiological anisocoria, Horner syndrome, Adie pupil, pharmacological anisocoria, third nerve palsy).

Keywords::

• Adie pupil
• anisocoria
• apraclonidine
• cocaine
• Horner syndrome
• hydroxyamphetamine
• pilocarpine
• third nerve palsy