Fexofenadine in pediatrics: oral tablet and suspension formulations

Abstract

Allergic rhinitis is a common chronic condition in children. Oral antihistamines are a first-line treatment option in allergic rhinitis and different formulations are available to aid administration to children. The tablet formulation of the second-generation antihistamine fexofenadine has established efficacy and safety in both adults and children. To aid administration in young children, a new oral suspension formulation of fexofenadine has been developed, indicated for the relief of seasonal allergic rhinitis symptoms in children aged 2 – 11 years and for uncomplicated skin manifestations of chronic idiopathic urticaria in children aged 6 months – 11 years. Clinical studies have shown the oral suspension to have both bioequivalence with the 30-mg tablet formulation and a favorable safety and tolerability profile.

Keywords::

• allergic rhinitis
• children
• fexofenadine
• pediatric
• suspension formulation

Notes