Primary and secondary coronary heart disease prevention using statins: is targeting Adam or Eve equally effective?

Anna I Kakafika Aristotle University of Thessaloniki, Hippokration Hospital, Medical School, Second Propedeutic Department of Internal Medicine, Thessaloniki, Greece

Vasilios G Athyros Aristotle University of Thessaloniki, Hippokration Hospital, Medical School, Second Propedeutic Department of Internal Medicine, Thessaloniki, Greece

Konstantinos Tziomalos University College London, Royal Free Hospital campus, Department of Clinical Biochemistry (Vascular Prevention Clinic), Pond Street, London, UK +44 020 7830 2258; +44 020 7830 2235; [email protected]

Asterios Karagiannis Aristotle University of Thessaloniki, Hippokration Hospital, Medical School, Second Propedeutic Department of Internal Medicine, Thessaloniki, Greece

Dimitri P Mikhailidis University College London, Royal Free Hospital campus, Department of Clinical Biochemistry (Vascular Prevention Clinic), Pond Street, London, UK +44 020 7830 2258; +44 020 7830 2235; [email protected]

, MD FFPM FRCP FRCPath

Abstract

Women differ from men in terms of their cardiovascular disease risk. The existing data suggest that primary cardiovascular disease prevention treatment with a statin could be cost effective for women and men with a high cardiovascular disease risk. In secondary cardiovascular disease prevention both men and women seem to benefit equally from statin treatment. However, the relatively small number of women included in several statin trials has limited the evidence available. With regard to the question of whether Eve is becoming Adam, the answer is not yet: we need more evidence!

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Primary and secondary coronary heart disease prevention using statins: is targeting Adam or Eve equally effective?

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Primary and secondary coronary heart disease prevention using statins: is targeting Adam or Eve equally effective?

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