Abstract
Background: Testosterone supplementation is a standard treatment for young men with hypogonadism and has also been advocated as a treatment for symptomatic older men with low testosterone levels. Several modes of testosterone replacement are available including capsules, patches, injections, buccal tablets and gels. Objective: To review the literature concerning therapeutic efficacy and potential limitations of testosterone gels. Methods: The FDA medical reviews and the computerised database PubMed were searched for clinical trials studying currently approved testosterone gels. Results/conclusions: Testosterone gel has proved to be a valuable contribution to the existing modes of testosterone treatment, combining therapeutic efficacy, convenience and safety.
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