Abstract
The use of bacteria for anticancer purposes was first attempted over 100 years ago. Recently, several strains of Salmonella have been shown to possess anticancer activity and, interestingly, Salmonella possesses a unique propensity to track to tumour tissue invivo. This review presents the use of Salmonella for cancer im-munotherapy, including the distinguishing characteristics of this organism and preclinical as well as clinical data.