Emerging treatments forallergic rhinitis

Abstract

Allergic rhinitis has increased in prevalence and afflicts almost a fourth of the younger population in westernised countries. Recent discoveries concerning the pathophysiology of the allergic reaction have led to an increase in research for new and improved remedies for allergic rhinitis. Pharmacological research in the field of allergic rhinitis concentrates on selective agents that may block or inhibit the release or actions of certain mediators or cytokines. The complexity of the allergic inflammatory process, however, may question the benefit of this research, unless the drug interferes early in allergic processes. Current treatments such as antihistamines and intranasal steroids can also be improved, displaying better clinical potency with fewer side effects. All novel treatments, however, must measure up with the present ones, in terms of both clinical and cost effectiveness.

• allergic rhinitis
• glucocorticosteroids
• histamine
• IgE
• immunotherapy
• leukotriene