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Editorial

Mechanisms of action of statins in stroke

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Pages 273-278 | Published online: 14 Feb 2007
 

Abstract

Statins decrease the incidence of cardiovascular events and death in patients with coronary artery disease. Moreover, the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) study has recently demonstrated that high-dose atorvastatin may also reduce the recurrence of stroke in patients with previous stroke or transitory ischemic attack.

Acknowledgements

The works of authors cited in the text were supported by grants from Fundación Ramón Areces, Fondo de Investigaciones Sanitarias (05/0451), Cardiovascular Nework (RECAVA-II), Fundación Española del Corazón, Fundación Mutua Madrileña, Ministerio de Educación y Ciencia (SAF 2004/06109), CAM (GR/SAL/0411/2004), MH02541A8640, Pfizer, Spain (Grant Pfizer SEA 2001) and CAM (S-GEN/0247/2006).

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