Declaration of interest
This work was supported by NIH PO1-CA090381, DOD PCRP Transformative Award W81XWH-13-2-0093, Veterans Affairs Research Service, and PNW Prostate SPORE-CA097186. SR Plymate has acted as scientific advisor for ESSA Pharma and Astellas Pharma. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.