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Expert Review of Anticancer Therapy Volume 1, 2001 - Issue 2
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Review

Pharmacogenetics of cytotoxic drugs

Ann K Daly Departments of Pharmacological Sciences, University of Newcastle, Medical School, Framlington Place, Newcastle-upon-Tyne, NE2 4HH, UK. [email protected]
&
Andrew G Hall Departments of Pharmacological Sciences, University of Newcastle, Medical School, Framlington Place, Newcastle-upon-Tyne, NE2 4HH, UK. [email protected]
Pages 301-308 | Published online: 10 Jan 2014
 
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Abstract

The main genetic polymorphisms affecting the metabolism and transport of cytotoxic drugs are discussed in this review. Likely future approaches to pharmacogenetics and emerging technologies, such as tumor classification using microarray analysis, are also considered.

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