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Abstract
Defined by its high level of accuracy and rapid radiation dose fall-off, radiosurgery has emerged as an effective radiation technique over the past few decades. Although it was once limited to conditions of the brain, head and neck regions, technological advances in computing and imaging have allowed the application of radiosurgery to conditions throughout the entire body. Using advanced imaging and robotics, the CyberKnife® (Accuray, Inc., Sunnyvale, CA, USA) is one of few systems capable of delivering radiosurgery with exquisite accuracy to tumors, cancers and other conditions throughout the body. This review focuses on the development, technology, clinical efficacy and future directions of the CyberKnife.
Acknowledgement
The authors thank Suzanne Robinson for her assistance during the development of the manuscript.
Financial & competing interests disclosures
Iris C Gibbs and Scott G Soltys are members of the Cyberknife® Society and have received honoraria for clinical presentations from Accuray, Inc., the manufacturer of Cyberknife®. Iris C Gibbs is a member of the Clinical Advisory Board of Accuray, Inc. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.