Abstract
Tobacco use is the leading preventable cause of death in the USA and will soon be the leading cause of preventable death worldwide. The only way to decreasetobacco-related morbidity and mortality in the short term is to help current smokers quit. Fortunately, effective clinical- and population-based interventions that increase tobacco cessation exist. However, these interventions are not being implemented, leaving most smokers to use the least effective approach to cessation (an unassisted quit attempt). This review summarizes the evidence for the effectiveness of clinical- and population-based interventions and recommendations from various organizations regarding tobacco use treatment. It also outlines proposed strategies for improving clinical and public health practice to increase tobacco cessation.