Continuous patient engagement in cardiovascular disease clinical comparative effectiveness research

ABSTRACT

Researchers have produced evidence that identifies interventions that reduce cardiovascular disease (CVD) risk; however, despite a significant investment in research CVD remains the leading cause of death. Engaging patients in the research process has the potential to ensure that evidence-based treatments are adopted in real-world practice to improve patient outcomes. The Patient-Centered Outcomes Research Institute has created an Engagement Rubric to guide meaningful engagement in the research process. A 10-step systematic framework to enhance patient engagement throughout the comparative effectiveness research process also has been proposed. This special report identifies the relationship between these two approaches to patient engagement and describes examples of how patients could be engaged in a hypothetical CVD study.

KEYWORDS:

• clinical comparative effectiveness research
• patient engagement
• patient-centered outcomes research
• engagement rubric
• cardiovascular disease

Acknowledgements

The authors would like to thank their PATIENTS Program partners Gail Betz, Cynthia Chauhan and Del Price for their generous support and input throughout the conceptualization and development of this manuscript.

Declaration of interest

This manuscript is supported by an Agency for Healthcare Research and Quality (AHRQ) Infrastructure Development Program in Patient-Centered Outcomes Research (PCOR) R24 grant entitled, ‘PATIENTS: PATient-centered Involvement in Evaluating effectiveNess of TreatmentS.’ Source: AHRQ [1R24HS022135]. The findings and conclusions in this manuscript are those of the authors, who are responsible for its content, and do not necessarily represent the views of AHRQ. No statement in this manuscript should be construed as an official position of AHRQ or of the U.S. Department of Health and Human Services. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.