12
Views
1
CrossRef citations to date
0
Altmetric
Review

Surgical treatment of Parkinson’s disease: ablation, stimulation and transplantation

Pages 239-246 | Published online: 10 Jan 2014
 

Abstract

Clinicians now have an extensive and effective pharmacopeia to treat the symptoms of Parkinson’s disease – especially in the early and moderate stages of the disorder. Ultimately, a significant number of patients with the disorder find that, as their disease progresses, pharmacotherapy fails to control symptoms or produces unacceptable adverse effects as higher medication doses are used. For patients with Parkinson’s disease whose symptoms are insufficiently controlled by medical therapy, surgical treatments can reduce symptoms, enhance functional capacity and sometimes reduce medication requirements. This article reviews the current state-of-the-art in surgical interventions for Parkinson’s disease, with an emphasis on deep brain stimulation therapy, an evolving treatment that accomplishes symptom control in a reversible, adjustable and nondestructive manner.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.