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Abstract
Headache in general represents a major public health problem with a magnitude that has not been fully acknowledged until recently. While the percentage of the global adult population with migraine is approximately 10%, other forms of unilateral headaches such as cluster headache, paroxysmal hemicrania, hemicrania continua and short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) syndrome are very rare. These headaches cause disability, suffering and loss of quality of life that easily compares to that of other chronic disorders. Continuous scientific research works towards a better understanding of these disorders and has accomplished a greater insight into the underlying pathophysiological mechanisms. This has led to improved treatment strategies in primary patient care that may prevent prolonged suffering of affected patients in the future.
Financial & competing interests disclosure
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
No writing assistance was utilized in the production of this manuscript.