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Abstract
The discrepancy between the number of patients on the waiting list and available donor hearts has led to the successful development of left ventricular assist devices (LVAD) as a bridge to transplantation. The conventional LVADs are designed to provide full hemodynamic support for the end-stage failing heart. However, full-support LVAD implantation requires major surgery, sternotomy and cardiopulmonary bypass in majority of cases. The Synergy Micro-pump is the smallest implantable LVAD and provides partial flow support up to 3 l/min. It was shown that early intervention with this device can provide substantial benefits to patients with severe heart failure not yet sick enough for a full-support LVAD. Due the small dimensions it can be implanted without cardiopulmonary bypass or a sternotomy. The purpose of this article is to review the clinical use of the Synergy Micro-pump as partial hemodynamic support.
Financial & competing interests disclosure
The authors AR Simon and AF Popov received consultancies fees from CircuLite. The remaining authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
No writing assistance was utilized in the production of this manuscript.
The outstanding advantage of Synergy Micro-pump is its subcutaneous location, permitting easy access through a right infra-clavicular incision leading to easy implantation, explantation and exchange of the micro-pump in comparatively less time.
Access though sternotomy post-Synergy implantation remains unhindered, which helps easy access to pericardial structures at the time of heart transplantation.
The system required and is currently undergoing an upgrade that shall resolve the issues involved with current system.
Endovascular implantation, right ventricular partial support and pediatric use of CircuLite Micro-pump system in the future may redefine the concept of long-term mechanical circulatory support.