Abstract
Vulval intraepithelial neoplasia (VIN) is a preinvasive vulval skin disorder, which is divided into VIN usual-type (associated with human papillomavirus [HPV]) and differentiated VIN (not associated with HPV). Traditionally, VIN has been treated by surgical excision or ablation, but various nonsurgical therapies have been investigated in order to preserve vulval skin and sexual function, as well as to specifically target HPV infection. This review evaluates the evidence for and against the effectiveness of current medical therapies for usual-type VIN.
Financial & competing interests disclosure
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
No writing assistance was utilized in the production of this manuscript.